THE EPINEPHRINE THAT
DEEP POCKETS
SYMJEPI® (epinephrine) Injection is affordable, portable, and simple, so you’re ready in case of an allergy emergency1-4
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WAC, wholesale acquisition cost. Prices as of February 1, 2022.
Each ready-to-use SYMJEPI Injection device delivers a full dose of epinephrine for the treatment of Type 1 allergic reactions, including anaphylaxis, to3:
SYMJEPI can be used to treat idiopathic anaphylaxis or exercise-induced anaphylaxis as well.3
SYMJEPI 0.3 mg is for patients who weigh approximately 66 lb (30 kg) or more.3
SYMJEPI 0.15 mg is for patients who weigh 33 lb to 66 lb (15 kg to 30 kg).3
When ready to use SYMJEPI, pull cap off to expose needle.
To ensure epinephrine does not leak by accident, do not touch the plunger until the needle is fully inserted.
While in a seated position, hold the device by the finger grips. Face the needle downward and slowly insert into the thigh.
SYMJEPI can be injected through clothing if necessary.
After needle is in the thigh, push the plunger all
the way down until it clicks. Hold for 2 seconds. Remove syringe and massage the area for 10 seconds.
The correct dose has been injected if the plunger has been pushed all the way down and the solution window is at least partially blocked.
Once the injection has been given, use one hand—with your fingers behind the needle—to slide the safety guard up until it clicks to cover the needle.
You may need a second SYMJEPI injection if symptoms continue or recur. More than 2 doses in a row should only be administered under direct medical supervision.
IMPORTANT NOTE: SYMJEPI should ONLY be injected into the middle of the outer thigh. Do not inject into the vein, buttock, fingers, toes, hands, or feet. If an accident happens and you inject SYMJEPI into another part of your or your child’s body, seek medical attention immediately.
The SYMJEPI Injection device is smaller than the most widely used EAI, making it easier for patients to carry it with them when they're on the go.6
Each device delivers 1 dose of epinephrine in an allergic emergency, including
anaphylaxis. The window gives you confidence that the medicine has been delivered.3†
Some medicine may remain in the device, but the correct dose has been injected if the plunger has been pushed all the way down and the window is at least partially blocked.3
SYMJEPI has a thinner needle than the most widely used EAI.6
SYMJEPI features a safety guard to keep you protected. Don’t forget to slide it up to cover the needle before putting the used SYMJEPI device back in its case.3
SYMJEPI comes as a 2-pack in a convenient carrying case that can be separated if needed.3
The epinephrine in SYMJEPI is light sensitive and should be stored in the case provided between 68°F and 77°F (20°C and 25°C).3
Because SYMJEPI is not an EAI, it’s important to specify explicitly what you are prescribing to your patients on their prescriptions.3
If writing for SYMJEPI specifically, don’t forget to include 1 of the following:
With severe allergies, preparation is the key to knowing how to react in an emergency. When you prescribe SYMJEPI to your patients, they gain access to tools designed to help them stay prepared.7
The SYMJEPI training device features a fake needle and no medication so your patients and their caregivers can practice with the device before ever needing to use it.
Order one for your office.
NOTE: If you are affiliated with a hospital or institution, please contact your USWM representative to have a SYMJEPI demonstrator delivered to you. If you do not have a contact, order one here.
The SYMJEPI Savings Program supports your eligible patients
with their out-of-pocket expenses‡
Offer is not insurance and is not valid for patients who are
enrolled in Medicaid, Medicare, TRICARE, or any other similar state-funded or federally funded programs
The actual savings on out-of-pocket costs for SYMJEPI will vary according to quantity, personal healthcare insurance coverage, and adherence to FDA dosing guidelines. For more information about the SYMJEPI Savings Program, please review the Terms and Conditions on SYMJEPI.com
Patients without insurance coverage of SYMJEPI will receive up to $100 off each SYMJEPI prescription filled. Maximum benefits per claim apply: $200 maximum for insured, covered patients; $100 maximum benefit for insured, not covered, and not insured/cash payments. Offer applies to a maximum 6 (2 packs) per claim. Annual maximum benefit is $1000. Any additional amounts due are your responsibility
Offer is not insurance and is not valid for prescriptions purchased under Medicaid, Medicare, TRICARE, or any other similar state-funded or federally funded programs. Patients must visit a participating pharmacy for savings or rebates on their SYMJEPI prescriptions. Maximum benefits may apply. The actual savings on out-of-pocket costs for SYMJEPI will vary according to quantity, personal healthcare insurance coverage, and adherence to FDA dosing guidelines. For more information about the SYMJEPI Savings Program, please review the Terms and Conditions.
As we want every patient who needs SYMJEPI to have access to it, we have developed the US WorldMeds Patient Assistance Program (UPAP), which will provide SYMJEPI to those patients who meet certain income and other eligibility requirements.*
Download the US WorldMeds Patient Assistance Program Application and provide it to your patients without health insurance whom you think may be eligible for the program.
For more information about UPAP, contact us at 877-438-9759 or 218-444-8217.
Patients whose prescriptions are paid in part or in whole by Medicare, Medicaid, or any similar federal or state healthcare program, are not eligible for this program.
SYMJEPI is indicated in the emergency treatment of allergic reactions (Type 1) including anaphylaxis to stinging insects (e.g., order Hymenoptera, which include bees, wasps, hornets, yellow jackets and fire ants) and biting insects (e.g., triatoma, mosquitoes), allergen immunotherapy, foods, drugs, diagnostic testing substances (e.g., radiocontrast media) and other allergens, as well as idiopathic anaphylaxis or exercise-induced anaphylaxis.
Contraindications
None.
Warnings and Precautions
Adverse Reactions
Adverse reactions to epinephrine include anxiety, apprehensiveness, restlessness, tremor, weakness, dizziness, sweating, palpitations, pallor, nausea and vomiting, headache, and/or respiratory difficulties.
Drug Interactions
Use in Specific Populations
Elderly patients may be at greater risk of developing adverse reactions.
Please see full Prescribing Information for SYMJEPI.
To report SUSPECTED ADVERSE REACTIONS, contact Adamis Pharmaceuticals Corporation at
References: 1. FDA drug shortages. US Food & Drug Administration. Accessed October 8, 2020. https://www.accessdata.fda.gov/scripts/drugshortages/dsp_ActiveIngredientDetails.cfm?AI=Epinephrine%20Injection,%20Auto-Injector&st=c&tab=tabs-1#. Accessed October 8, 2020. 2. Symjepi [Prescribing Information]. San Diego, CA: Adamis Pharmaceuticals Corporation; 2019. 3. Moss RB, Daniels K, Moll T, Carlo DJ. Human factors study in untrained adolescents comparing a recently approved single-dose epinephrine prefilled syringe with an approved autoinjector. Ann Allergy Asthma Immunol. 2018;120(5):540-541. 4. Stecher D, Bulloch B, Sales J, Schaefer C, Keahey L. Epinephrine auto-injectors: is needle length adequate for delivery of epinephrine intramuscularly? Pediatrics. 2009;124(1):65-70. 5. Anaphylaxis. American Academy of Allergy Asthma & Immunology website. https://www.aaaai.org/conditions-and-treatments/allergies/anaphylaxis. Accessed October 8, 2020.
Warnings and Precautions
